en گروه سرامیک Ceramic Materials and Engineering Research Paper Research Paper In this research, the nanostructured titania-coated silica microsphere (NTCSM) membrane consisting of titania-silica core-shell particles on &alpha;&ndash;alumina substrate was prepared by dip-coating method. The silica microspheres were synthesized by the St&ouml;ber method, and the nanostructured titania shell was obtained from a polymeric sol. Then, the prepared core-shell particles were deposited on alumina substrates. The samples were characterized by DLS, TG-DTA, XRD, FTIR and SEM. The photo-catalytic activity of the NTCSM membranes was evaluated using photo-degradation of methyl orange solution by UV&ndash;visible spectrophotometer. Also, physical separation capability was investigated by filtration experiment based on methyl orange removal from aqueous solution using a membrane setup. The mean particle size distribution of silica microspheres was determined to be about 650 nm that by deposition of titania nano-particles increased up to about 800 nm. After 60 min UV-irradiation, the dye removal efficiency was determined to be 80% by the membrane. By coupling separation process with photo-catalytic technique, the removal efficiency was improved up to 97%. Thus, the NTCSM membranes showed simultaneous photo-degradation and separation capabilities for dye removal from water.<br> &nbsp; Membrane, Nanostructured TiO2, SiO2 microsphere, Titania-silica, Photo-degradation, Separation 35 44 http://ijmse.iust.ac.ir/browse.php?a_code=A-10-1740-1&slc_lang=en&sid=1 V. Tajer Kajinebaf vtajer@yahoo.com 180031947532846009656 180031947532846009656 Yes Department of Materials Engineering, Takestan Branch, Islamic Azad University, Takestan, Iran M. Zarrin Khame-Forosh m.zarrinkhame@gmail.com 180031947532846009657 180031947532846009657 No School of Metallurgy and Materials Engineering, Iran University of Science & Technology, Tehran, Iran H. Sarpoolaky hsarpoolaky@iust.ac.ir 180031947532846009658 180031947532846009658 No School of Metallurgy and Materials Engineering, Iran University of Science & Technology, Tehran, Iran